Efficient operation and shared utilization of large-scale research instruments in the biomedical field, including Bio-HVEM and 7T MRI systems
- Development of advanced analytical science technologies in ultra-high-resolution bioimaging and translational research based on collaboration among academia, industry, research institutes, and hospitals
Research Content
Bio-EM imaging translational research
Analysis of two-dimensional and three-dimensional ultrastructures of cells and tissues, as well as structural analysis of proteins and protein complexes under cryogenic conditions
- Ultra-high-resolution large-area analysis using electron tomography and large-area imaging techniques
MRI imaging translational research
Performs image acquisition, develops data analysis methods, and supports collaborative research using MRI systems (3T, 7T, and 9.4T) capable of high-resolution three-dimensional imaging of humans and animals
- Research on high-field MRI systems and the development of brain functional imaging acquisition and analysis techniques
- Research on brain metabolomics analysis using high-field MRI
- Translational research on animal and human diseases using MRI
Research Infrastructure
Bio-EM imaging translational research
Conducts collaborative research with leading domestic and international partners from academia, industry, research institutes, and hospitals using the Bio-HVEM system combined with electron tomography and LLM-based analysis techniques
- Two-dimensional and three-dimensional ultrastructural analysis and modeling of organelles, cells, and tissues
- Tracking and distribution analysis of specific proteins in cells and tissues using immuno-electron microscopy (Immuno-EM) and multimodal imaging
- Cryogenic sample preparation using a cryo-ultramicrotome (Cryo-UT) and high-pressure freezing (HPF)
Bio-EM imaging translational research
MRI imaging translational research
- Development of imaging techniques and analytical methods using 7T, 9.4T, and 3T MRI systems
- Specialized research using (ultra) high-field instruments such as 7T and 9.4T
* Including research such as fMRI, MRS, CEST, QSM, angiography, and RF field numerical analysis
- MRI-based research on biological diseases in animals and humans
- Identification of biomarkers for neuropsychiatric and vascular diseases and validation of the effects of current density imaging
* Including studies on depressive disorders, stroke, Parkinson’s disease, and non-invasive deep brain stimulation techniques
MRI imaging translational research
